Product Name :
VPS4a Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
hVPS4 antibody Protein SKD2 antibody SKD1 antibody SKD1 homolog antibody SKD1A antibody SKD2 antibody Vacuolar protein sorting 4 homolog A antibody Vacuolar protein sorting 4 yeast homolog of 展开
Function :
Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses).4-Formylbenzenesulfonyl chloride In stock Involved in cytokinesis.6-Bromo-8-iodoquinolin-2(1H)-one Price
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human VPS4a 351-437/437
Species reactivity:
Human, Mouse, Rat, Dog, Pig, Rabbit
Verify application:
WB, ELISA, IHC-P, IF
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.PMID:33661722 Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
48 KDa
Positive control :
Ubiquitously expressed.