Product Name :
1,2-Naphthoquinone (CAS 524-42-5)
Synonym :
β-Naphthoquinone
Application :
1,2-Naphthoquinone is a useful naphthalene for proteomics research
CAS:
524-42-5
Purity:
≥96%
Molecular Weight:
158.15
Formula :
C10H6O2
Physical state:
Solid
solubility :
Soluble in methanol, alcohol, benzene, and ether. Insoluble in water.
Shipping Condition :
Store at room temperature
Melting point:
139-142° C (lit.)(dec.)
SMILES:
C1=CC=C2C(=C1)C=CC(=O)C2=O
References:
:[Chemical biology of 1,2-naphthoquinone, a novel air pollutant that affects signal transduction pathways]. | Sumi, D. and Kumagai, Y. 2007. Yakugaku Zasshi. 127: 1949-56. PMID: 18057784Synthesis, characterization and antiproliferative activity of 1,2-naphthoquinone and its derivatives. | Shukla, S., et al. 2012. Appl Biochem Biotechnol. 167: 1430-45. PMID: 22258648Redox cycling of 1,2-naphthoquinone by thioredoxin1 through Cys32 and Cys35 causes inhibition of its catalytic activity and activation of ASK1/p38 signaling. | Shinkai, Y., et al. 2012. Chem Res Toxicol. 25: 1222-30. PMID: 22587396Photochemical Reaction Between 1,2-Naphthoquinone and Adenine in Binary Water-Acetonitrile Solutions. | Zhou, Q., et al. 2018. Photochem Photobiol. 94: 61-68. PMID: 28710892Formation of Bulky DNA Adducts by Non-Enzymatic Production of 1,2-Naphthoquinone-Epoxide from 1,2-Naphthoquinone under Physiological Conditions. | Matsui, T., et al. 2019. Chem Res Toxicol. 32: 1760-1771. PMID: 31430133Molecular mechanism and health effects of 1,2-Naphtoquinone. | Soares, AG., et al. 2020. EXCLI J. 19: 707-717. PMID: 32636724Investigation by mass spectrometry and 32P post-labelling of DNA adducts formation from 1,2-naphthoquinone, an oxydated metabolite of naphthalene. | Clergé, A., et al. 2021. Chemosphere. 263: 128079. PMID: 332970781,2-Naphthoquinone as a Poison of Human Type II Topoisomerases. | Collins, JA. and Osheroff, N. 2021. Chem Res Toxicol. 34: 1082-1090. PMID: 33760604Understanding the evolution of a de novo molecule generator via characteristic functional group monitoring. | Fujita, T., et al. 2022. Sci Technol Adv Mater. 23: 352-360.Price of 1196153-26-0 PMID: 35693890A New 1,2-Naphthoquinone Derivative with Anti-lung Cancer Activity.1831130-33-6 site | Nakagawa, R.PMID:33483732 , et al. 2022. Chem Pharm Bull (Tokyo). 70: 477-482. PMID: 35786566High-performance paper-based biocathode fabricated by screen-printing an improved mesoporous carbon ink and by oriented immobilization of bilirubin oxidase. | Loew, N., et al. 2022. Sci Rep. 12: 14649. PMID: 36030337[Molecular mechanism of EGFR signaling evoked by environmental pollutant 1,2-naphthoquinone]. | Tsuchida, T. and Uehara, T. 2022. Nihon Yakurigaku Zasshi. 157: 352-355. PMID: 36047152Sustainable Synthesis, Antiproliferative and Acetylcholinesterase Inhibition of 1,4- and 1,2-Naphthoquinone Derivatives. | Cabral, RG., et al. 2023. Molecules. 28: PMID: 36770899Subchronic exposure to 1,2-naphthoquinone induces adipose tissue inflammation and changes the energy homeostasis of mice, partially due to TNFR1 and TLR4. | Oliveira Ferreira, CK., et al. 2023. Toxicol Rep. 11: 10-22. PMID: 37383489